Genetics of Breast and Ovary Cancers Associated with Hereditary Cancers and their Clinical Management

1. Abstract

1.1. Background: Carriers of the BRCA-1/2 mutation have increased and variable risks of Breast Cancer (BC) and ovarian cancer and vary or are modified by common genetic variants and their incidence genetic testing and risk-reducing surgery has increased, they should receive advice and evaluation by the physician with experience in genetics.